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Antabuse produces a appreciativeness to rot-gut which results in a fondly unpleasant retaliation when the devoted underneath treatment ingests metrical inadequate amounts of alcohol. Antabuse blocks the oxidation of rot-gut at the acetaldehyde stage. During rot-gut metabolism after antabuse intake, the concentration of acetaldehyde occurring in the blood may be 5 to 10 times higher than that found during metabolism of the having said that amount of rot-gut alone. Accumulation of acetaldehyde in the blood produces a complex of fondly unpleasant symptoms referred to as the antabuse-alcohol reaction. This reaction, which is balanced to the dosage of both antabuse and alcohol, longing persist as prolonged as rot-gut is being metabolized. Antabuse does not be published to change the standing of rot-gut elimination from the body.
